Searchable abstracts of presentations at key conferences in endocrinology

ea0056p233 | Calcium & Vitamin D metabolism | ECE2018

Association of vitamin D status with pulmonary function: potential mediation by physical function and inflammation

Rafiq Rachida , van Schoor Natasja , Lips Paul , den Heijer Martin , Spruit Martijn , de Jongh Renate

Background: Several studies have reported an association between serum 25-hydroxyvitamin D (25(OH)D) concentrations and pulmonary function in the general population. However, results remain conflicting. In addition, the underlying mechanisms by which vitamin D affects pulmonary function are unknown.Objective: To assess the relationship of vitamin D status with pulmonary function and whether this relationship is mediated by physical function and/or inflam...

ea0041oc11.5 | Bone & Calcium Homeostasis | ECE2016

Effects of vitamin D supplementation on respiratory muscle strength and physical performance in patients with COPD: a pilot trial

Rafiq Rachida , Prins Henk-Jan , Boersma Wim , Daniels Hans , den Heijer Martin , Lips Paul , de Jongh Renate

Introduction: Although vitamin D is well known for its function in calcium homeostasis and bone mineralisation, several studies have shown an effect on physical function and muscle strength. Also, vitamin D has been associated with pulmonary function and the incidence of airway infections. As vitamin D deficiency is highly prevalent in COPD-patients, supplementation might have a beneficial effect in these patients.Objective: To assess the effect of vitam...

ea0056oc6.5 | Genetic and environmental determinants of obesity and insulin resistance | ECE2018

Associations of different body fat deposits with serum 25-hydroxyvitamin D concentrations

Rafiq Rachida , Walschot Floor , Lips Paul , Lamb Hildo , de Roos Albert , Rosendaal Frits , den Heijer Martin , de Jongh Renate , de Mutsert Renee

Introduction: Overall and abdominal obesity are both well-established risk factors of vitamin D deficiency. However, it is unclear which fat depot is most strongly related to serum 25-hydroxyvitamin D (25(OH)D) concentrations.Objective: This study aims to distinguish specific contributions of total body fat, abdominal subcutaneous adipose tissue (aSAT), visceral adipose tissue (VAT) and hepatic fat on 25(OH)D concentrations.Methods...